However, since there is no effect of rapamycin on the size of the soleus muscle or the size of the Type I fibers of the gastrocnemius muscle, the effect of rapamycin on the size of slow-twitch muscle may not be significant. 3.
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Rapamycin administration causes a decrease in muscle contractile function and systemic glucose intolerance concomitant with reduced skeletal muscle Rictor, the mTORC2 component, expression independent of energy intake in young rats.
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