Interleukin-6 as a critical inflammatory marker for early diagnosis of surgical site infection after spine surgery.

The binary logistic regression analysis using only IL-6 POD7 showed a highly significant regression coefficient (OR = 1.10; 95% CI 1.05–1.16; P = 0.0002), an AUC of 0.86 (95% CI 0.75–0.97; P < 0.001), a Nagelkerke’s R 2 of 0.29, and a strong effect with Cohen’s f 2 of 0.40 (Fig. 1 A).

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