borderline significantP = .055
Prognostic Risk Factors In univariate Cox models of other prognostic risk factors, OS was positively associated with MGMT methylation (hazard ratio [HR] 0.490 [CI: 0.314–0.765], P = .002 [.005]) and borderline significant negatively associated with steroid use (HR 1.562 [CI: 0.991–2.463], P = .055 [.093]), but not with PS (HR 1.284 [CI: 0.841–1.959], P = .247 [.344]), age (HR 0.992 [CI: 0.969–1.107], P = .528 [.638]), an a priori diagnosis of progression (HR 1.304 [CI: 0.845–2.012], P = .230 [.332]), or prior biopsy only (HR 0.53 [CI: 0.263–1.062], P = .073 [.119]).