Hyperpolarized [1-<sup>13</sup>C]pyruvate cardiovascular magnetic resonance imaging identifies metabolic phenotypes in patients with heart failure.

Subgroup analyses showed that correlations between LVEF and metabolite ratios were highly significant in the IHD group; lactate/bicarbonate (r = −0.9, p = 0.01); lactate/TC (r = −0.9, p = 0.01); and bicarbonate/TC (r = 0.8, p = 0.03) ( Fig. 2 ).

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