Fabrication of Bioactive <i>Helix aspersa</i> Extract-Loaded Chitosan-Based Bilayer Wound Dressings for Skin Tissue Regeneration.

However, NIH/3T3 fibroblast cell proliferation showed a decreasing trend at the 14th day for all groups due to the mucoadhesive property of the extracts on the material surface, leading to cell colonization and preventing spreading.

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Results showed that the water uptake capacity of all porous and bilayer groups showed an increasing trend up to an incubation period of 48 h.

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