Atypical fractures at non-classical sites associated with anti-resorptive therapy: a systematic review.

1 Osteoporotic fractures are highly significant, leading to persistent pain and increased mortality of over 30% within 1 yr following hip fractures. 2 Fragility fractures are estimated to cost the healthcare system more than €56 billion per annum in Europe alone. 3 Oral and intravenous bisphosphonates are anti-resorptive drugs that have been the most used treatments for osteoporosis globally for more than 30 yr.

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