Genetic Variants Linked to Opioid Addiction: A Genome-Wide Association Study.

However, two variants, rs6265 ( NC_000011.10 :g.27658369C>T) on BDNF , a missense coding variant (p.Val66Met in BNDF isoform a, previously reported [ 18 ]), and rs1799971, a missense variant on OPRM1 (c.118A > G) changing p.Asn40Asp in mu-opioid receptor (also previously reported [ 11 , 12 , 13 ]), have a raw p -value of <0.30, reflecting a nonsignificant trend.

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