In CCRF-CEM cells, cleaved caspase-3 levels showed an increasing trend with higher concentrations of Stattic, indicating enhanced apoptotic activity, although the changes were not statistically significant.
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Stattic suppresses p‑STAT3 and induces cell death in T‑cell acute lymphoblastic leukemia.
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The sentences
Meanwhile, p62 protein levels showed a decreasing trend at 24 h, although this change was not statistically significant, further supporting autophagy activation.