NAD-jumbo phages encode NAD-dependent enzymes for various biological processes Considering the crucial role of NAD + in various biological processes including DNA replication, DNA repairs, and redox reactions for all organisms [ 56 ], NAD + may be highly significant for the life cycle of NAD-jumbo phages.
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Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD<sup/>.
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