After treatment with miR-205-5p KD -hypo-Exos, p-AKT, p-mTOR and p-PI3K expression levels in ROMECs all showed a decreasing trend compared to hypo-Exos (Fig. 8 O and Q).
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Exosomes derived from hypoxic mesenchymal stem cells restore ovarian function by enhancing angiogenesis.
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As expected, after treatment with miR-205-5pOE-norm-Exos, p-AKT, p-mTOR and p-PI3K expression levels in ROMECs all showed an increasing trend compared to norm-Exos (Fig. 8 O and Q).