Global, regional, and national burden of acute lymphoblastic leukemia in children: Epidemiological trends analysis from 1990 to 2021.

From 1990 to 2021, only high-middle SDI areas showed an increasing trend in the EAPC of incidence rate (1.49; 95% CI, 1.08 to 1.91) ( Table 1 ; Figure 2 A).

also in 63,971 other papers

From 1990 to 2021, the global incidence rate showed a decreasing trend (EAPC, −0.48; 95% Confidence Interval [CI], −0.7 to −0.26), along with a decreasing trend in females (EAPC, −0.84; 95% CI, −1.07 to −0.61), while the EAPC in males did not change significantly (EAPC, −0.2; 95% CI, −0.41 to 0.01) ( Table 1 ).

also in 47,180 other papers