The endocannabinoid system in the brain undergoes long-lasting changes following neuropathic pain.

iScience · 2024 · PMC11664153 · PMID 39717086

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an increasing trendno p-value reported

Research on changes in CB2Rs levels is limited, and only an increasing trend in CB2R levels in the ventral hippocampus (vHIP) has been reported in CCI mice. 19 Furthermore, the activity of the ECS in the hippocampus can be regulated through exogenous drugs.

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