However, in patients continually treated with metformin, the incidence of Alzheimer’s disease might render a slightly increasing trend [ 73 , 74 ], and the association between metformin treatment and the risk of dementia events in patients with T2D have not been fully confirmed yet.
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Anti-diabetic agents and the risks of dementia in patients with type 2 diabetes: a systematic review and network meta-analysis of observational studies and randomized controlled trials.
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