Global, regional, and national burden of childhood cardiovascular disease: trends from 1990 to 2021.

Front Pediatr · 2024 · PMC11668807 · PMID 39722769

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an increasing trendno p-value reported

A negative upper limit of an EAPC and its confidence interval suggests a declining trend in rates, whereas a positive lower limit indicates an increasing trend.

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a decreasing trendno p-value reported

From 1990 to 2021, the IR of childhood CVD in children under 5 years of age showed a decreasing trend, while the IR in children aged 10–14 years showed a continuous increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.