While a decreasing trend was observed in the proportion of Gabra2 expressing Drd2+ MSNs from P2 to P9, neither this difference nor changes between P9 and P16 were statistically significant ( Figure 4C and Table 2 , middle panel).
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Early developmental changes in GABAA receptor expression in nucleus accumbens medium spiny neurons.
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GABRA1 expression in the human striatum follows a slightly increasing trend from prenatal to early postnatal developmental period, similar to the trend observed in mice in the current study ( Supplementary Figure S4A ).