Retrospective analysis on the outcomes of contact lens-associated keratitis in a tertiary centre: an evidence-based management protocol to optimise resource allocation.

Our results support the safe use of fluoroquinolone monotherapy as first-line treatment which is proven by recent UK studies showing an increasing trend of resistance against penicillin in Gram-positive and Gram-negative bacteria but a maintained moderate and high susceptibility to fluoroquinolone, respectively. 17 31 32 Moorfields Eye Hospital’s local recommended empirical regime for CLAKs have been modified to hourly preservative-free moxifloxacin 0.5% for 48 hours, then hourly during the day for 3 days, and four times daily for 7 days.

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