Combined MRI, high-resolution manometry and a randomised trial of bisacodyl versus hyoscine show the significance of an enlarged colon in constipation: the RECLAIM study.

Gut · 2024 · PMC11671975 · PMID 39438126

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

just failed to reach significancep=0.09so close (0.05 < p ≤ 0.1)

Thus only 33% of patients with enlarged colons were bisacodyl responders v 59% of those with normal colon volume but again this just failed to reach significance, Fisher’s exact test p=0.09.

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