PTGS2/GRP78 Activation Triggers Endoplasmic Reticulum Stress Leading to Lipid Metabolism Disruption and Cell Apoptosis, Exacerbating Damage in Bovine Mastitis.

Western blot data analysis results showed that the expression of IL-1β, IL-6, TNF-α, PTGS2, ATF6, PERK, GRP78, BAX, Bcl-2, Caspase3, and Caspase8 in the CM group was significantly or extremely significant compared with the NC group, and the protein level was consistent with the gene level, and the change trend was roughly consistent with that of MAC-T treated with LTA ( Figure 5 D,F,H).

also in 7,787 other papers