Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.

Furthermore, In the ALD group, the activities of ADH ( Figure 4B ) and ALDH ( Figure 4C ) decreased significantly compared to the Ctrl group, and the intervention of the two drugs in the experiment could reverse this decline ( p < 0.05) and this effect showed an increasing trend with the increase of LGS dosage.

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Furthermore, Verrucomicrobia and Actinobacteria displayed an increasing trend, while the phylum Desulfurococcales showed a decreasing trend, although these differences were not statistically significant.

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