Reduced gut microbiota diversity in ulcerative colitis patients with latent tuberculosis infection during vedolizumab therapy: insights on prophylactic anti-tuberculosis effects.

Examination of microbial changes in the colonic mucosa in specimens from surgical resections revealed a decreasing trend in the quantity of certain commensal bacteria [ 12 ].

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In patients with UC and LTBI who did not receive prophylactic anti-tuberculosis treatment, we observed changes in the intestinal microbiota before and after vedolizumab treatment, showing an increasing trend.

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