Reversal of Endothelial Cell Anergy by T Cell-Engaging Bispecific Antibodies.

Furthermore, after the 4 h adhesion assay, we also observed a quick and highly significant upregulation of EC adhesion molecules E-selectin, ICAM1, and VCAM1 in line with the known rapid TNFα-mediated induction kinetics of these adhesion molecules [ 34 , 35 ] ( Figure 4 D).

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