Development, Pre-Clinical Safety, and Immune Profile of RENOVAC-A Dimer RBD-Based Anti-Coronavirus Subunit Vaccine.

For example, the CD3+ve cell percentage in the treatment groups was significantly higher in the spleen for day 42, whereas in the lymph node, it showed a decreasing trend ( Figure 8 ).

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Nevertheless, an increasing trend in IFNγ levels reflects changes in IL-18 and CD3+ve + CD4+ve levels over corresponding days, suggesting that RENOVAC vaccination could also trigger Th1 cell responses crucial for the cellular immune system.

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