Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT-CHF (European) study with the ASIAN-HF registry.

By definition, there was a highly significant LVEF improvement of 19.7 ± 8.0% in patients with HFimpEF (29.8 ± 6.8% at baseline vs. 49.5 ± 5.7% at 9 months) as compared to patients with persistent HFrEF (Δ 2.4 ± 6.9%, 27.8 ± 7.2% at baseline vs. 30.2 ± 7.2% at 9 months) ( p < 0.001) ( Table 1 and Figure 1 ).

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