Phytochemical characterization and anti-arthritic potential of green-synthesized CuO nanoparticles derived from the <i>Bistorta amplexicaulis</i> root extract.

Negative control and high-dose NPs were found to exhibit a nonsignificant association, while all other groups were highly significant.

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Furthermore, a marginally nonsignificant association was found between the negative control and treatment group 3, as shown in Figure 12B . 3.8.5.12 Effect of green synthesized CuO nanoparticles from the B. amplexicaulis root extract on serum creatinine levels (mg/dL) The statistical analysis revealed a significant increase in creatinine levels ( p < 0.0001) in the standard treatment group compared to the negative control group.

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Additionally, a marginally significant relationship was found between the negative control and treatment group 3, as shown in Figure 12A . 3.8.5.11 Effect of green synthesized CuO nanoparticles from the B. amplexicaulis root extract on aspartate aminotransferase levels (U/L) Statistical analysis of aspartate aminotransferase (AST) levels indicated a significant increase ( p < 0.01) in the positive control group compared to the negative control group.

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