There was a highly significant enrichment of Cluster 0-like cells in the previously designated IL1β + cluster (4682 Cluster 0-like cells/7985 IL1β cells) compared to the rest of the dataset (1102 Cluster 0-like cells/52,706 Other cells, χ2 = 25707.926 p < 0.0001, Chi-squared test with Yates correction).
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Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma.
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