Global, regional and national burden due to retinoblastoma in children aged younger than 10 years from 1990 to 2021.

BMC Med · 2024 · PMC11686879 · PMID 39736662

Europe PMC DOI

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a decreasing trendno p-value reported

Conversely, an estimate with a 95% CI upper limit less than zero indicates a decreasing trend.

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an increasing trendno p-value reported

Statistically, an APC or AAPC estimate, with its 95% CI lower limit surpassing zero, indicates an increasing trend within the specified interval.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.