highly significantp=1.62×10 -12
Gene expression was consistently downregulated in all stages of KIRC compared to normal tissue, with highly significant p-values observed in stage 1 (p=1.62×10 -12 ), stage 2 (p=1.52×10 -11 ), stage 3 (p<1×10 -12 ), stage 4 (p=1.62×10 -12 ).