highly significantp = 1.68E-09
Among the targets of E2F8, 17 were present in the LP gene expression module (total 115 genes), including Gjb2 , Tmem150a , Wfdc2 , Maged1 , a statistically highly significant enrichment ( p = 1.68E-09 in a hypergeometric test) (Supplementary Fig. 13a ).