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L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer.

Nat Commun · 2025 · PMC11696420 · PMID 39747894

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We also observed a significant decreasing trend in SNAIL expression and an increasing trend in the expression of the SNAIL target genes OCLN , DSP and CLDN9 after L3MBTL3 was knocked out in MDA-MB-231 and SUM159PT cells (Fig. 5f ).

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