Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.

We found a highly significant, positive interaction (p < 0.001) effect between MAPK-pathway altered diffuse low-grade gliomas relative and clusters 1 and 2 (Fig. 3F , Supplementary Fig. 4 ), indicating over-representation of tumors with a higher expression of immune infiltrate-related genes with this tumor entity.

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