Fractionated low-dose radiotherapy primes the tumor microenvironment for immunotherapy in a murine mesothelioma model.

Cancer Immunol Immunother · 2025 · PMC11699009 · PMID 39751851

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an increasing trendno p-value reported

Although CD8 + to Treg ratios showed an increasing trend in favor of CD8 + cells in the LDRT group compared to the non-irradiated group, the differences were not statistically significant (Fig. 4 e).

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a decreasing trendno p-value reported

Although there was a decreasing trend in %sO 2 T over time, both the 2 Gy × 5 and 6 Gy × 2 fraction groups had greater %sO 2 T than the sham-irradiated group on all days.

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