Notably, we observed an interesting phenomenon in aged melanocytes and mesenchymal cells: The structural entropy of gene networks in these aged cells showed a decreasing trend compared to young cells, as shown in Fig. 6d .
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The network structural entropy for single-cell RNA sequencing data during skin aging.
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S7 , we observed an increasing trend in network structural entropy in aged differentiated keratinocytes, pericytes, secretory-papillary cells, and secretory-reticular cells.