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A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer.

Cancer Cell Int · 2025 · PMC11702187 · PMID 39757159

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The per residue root mean square fluctuation (RMSF) values revealed a decreasing trend for CXCR4 in complex with A1 compared to those in complex with ITD, which shows the tighter intercalations of A1 with CXCR4 (Supplementary Information, Figure S5).

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