highly significantp = 0.0005
In a multivariable analysis of EFS including pre-transplant IDDA v2.1 ≤ 14 / ≥15 and HCT-CI ≤ 2 / ≥3 and the interaction between these prognostic factors, as well as age at transplant and date of transplant, neither IDDA v2.1 ( p = 0.059, HR = 4.6) nor HCT-CI ( p = 0.057, HR = 7.1) were independently significant, but the interaction between these two factors combined (HCT-CI ≥ 3 and IDDA v2.1 ≥ 15) was highly significant ( p = 0.0005, HR = 18.0), Fig. 3 H.