Barely Significant
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Pre-Transplant Immune Dysregulation Predicts for Poor Outcome Following Allogeneic Haematopoietic Stem Cell Transplantation in Adolescents and Adults with Inborn Errors of Immunity (IEI).

J Clin Immunol · 2025 · PMC11703937 · PMID 39760904

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hedged sentence
0.0005
closest p · 0.0× alpha
0.0005
boldest claim

The sentences

highly significantp = 0.0005actually significant
In a multivariable analysis of EFS including pre-transplant IDDA v2.1 ≤ 14 / ≥15 and HCT-CI ≤ 2 / ≥3 and the interaction between these prognostic factors, as well as age at transplant and date of transplant, neither IDDA v2.1 ( p = 0.059, HR = 4.6) nor HCT-CI ( p = 0.057, HR = 7.1) were independently significant, but the interaction between these two factors combined (HCT-CI ≥ 3 and IDDA v2.1 ≥ 15) was highly significant ( p = 0.0005, HR = 18.0), Fig. 3 H.

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