Efficacy of Colchicine for Secondary Prevention of Stroke: A Systematic Review and Meta-Analysis of Randomized Control Trials.

Cureus · 2024 · PMC11706611 · PMID 39776745

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

borderline significantp = 0.05actually significant

The meta-analysis revealed a borderline significant 24% relative risk reduction in stroke incidence (risk ratio 0.76, 95% confidence interval 0.57-1.00, p = 0.05).

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borderline significanceno p-value reported

In conclusion, while our meta-analysis suggests a potential benefit of colchicine in stroke prevention, the borderline significance of the result calls for cautious interpretation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.