Alzheimer’s disease APOE neuropathology‐based score, amyloid, and ptau polygenic scores' association with amyloid PET positivity

The amyloid‐PGS was also significantly associated with A+ (OR = 0.492, P = 0.026), whereas the ptau‐PGS did not quite reach significance (OR = 3.218, P = 0.054).

also in 45 other papers

The significant association between amyloid‐PGS and A+, and near significance after adding the APOEscore, demonstrates the existence of additional genetic effects outside of APOE that have an impact on amyloid accumulation.

also in 127 other papers