Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes.

ORA of PC1 loadings using Gene Ontology of Biological Processes revealed highly significant enrichment of pathways involved in neuron development and differentiation as well as ion transmembrane transport ( Fig. 4 F), while PC2 loadings > 0.2 were enriched for processes involving inflammatory responses, the immune system and leukocyte activation ( Fig. 4 G).

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