Although a decrease in α-diversity indices compared with h -plaque 0 was detected, we observed an increasing trend from day 3 post-inoculum (Fig. 6 ) in richness and diversity, supported by Cohen’s effect size ( d ) (Supplementary Table 2 : h -plaque 0-native day 7 ( d obs.feat :1.24; d Shannon : 2.13; Simpson: 1.88) compared to h -plaque 0-day 3 ( d obs.feat : 6.46; d Shannon : 12.3; Simpson: 7.53).
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Underscoring long-term host-microbiome interactions in a physiologically relevant gingival tissue model.
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