A slight trend towards a lower increase in LET-weighted D2% in the brainstem was observed in plans with larger hinge angles, as depicted in Fig. 5 , although no statistically significant correlation was identified (Pearson correlation coefficient: −0.45, p = 0.22, excluding the plan with distal edges pointed towards the spinal cord).
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Variations in linear energy transfer distributions within a European proton therapy planning comparison of paediatric posterior fossa tumours.
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