MTHFR C677T rs1801133 and TP53 Pro72Arg rs1042522 gene variants in South African Indian and Caucasian psoriatic arthritis patients.

Genet Mol Biol · 2025 · PMC11721215 · PMID 39792433

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hedged sentence

0.0589

closest p · 1.2× alpha

0.0589

boldest claim

The sentences

marginally significantp = 0.0589so close (0.05 < p ≤ 0.1)

(i) MTHFR rs1801133: There was a marginally significant genotype distribution between all PsA patients and healthy controls (CC, CT, TT: 36%, 57%, and 7% versus 49%, 49%, and 2%; p = 0.0589), and PsA patients had a significantly higher frequency of the variant T-allele versus healthy controls (36% versus 26.5%; OR = 1.53, 95% CI = 1.01 - 2.31, p = 0.0477).

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