Creation of Long-Term Physical Stability of Amorphous Solid Dispersions N-Butyl-N-methyl-1-phenylpyrrolo[1,2-a]pyrazine-3-carboxamide, Resistant to Recrystallization Caused by Exposure to Moisture.

Materials (Basel) · 2025 · PMC11722151 · PMID 39795848

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a decreasing trendno p-value reported

SD PEG delaminated after storage, indicating its instability as an inhibitor of the crystallization of GML-3 molecules and the solubility dropped to 27.2% with a decreasing trend due to precipitation of GML-3 and not being able to PEG.

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