NFKB1 as a key player in Tumor biology: from mechanisms to therapeutic implications.

Cell Biol Toxicol · 2025 · PMC11724797 · PMID 39797972

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closest p

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an observed trendno p-value reported

For instance, an observed trend of gastric cancer formation in Nfkb1 − / − mice is closely correlated with the initiation of the JAK-STAT signaling pathway and increased expression of the PD-L1 immune checkpoint inhibitor (O'Reilly et al. 2018 ).

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may not be significantno p-value reported

However, the fact that the 95% confidence interval intersected 1 (95% CI: 0.99–9.77) suggests that this relationship may not be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.