Reversal of inflammatory reprogramming by vasodilator agents in pulmonary hypertension.

The reversal DEGs obtained from the dataset for each cell type were highly significant, based on empirical null distribution (B cells: n=24, p-value <2.2×10 −16 ; CD4+ T cells: n=67, p-value <2.2×10 −16 ; CD8+ T cells: n=108, p-value <2.2×10 −16 ; monocytes: n=183, p-value <2.2×10 −16 ; NK cells: n=66, p-value <2.2×10 −16 ) ( supplementary figure S5a–e ).

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