Dasatinib and Quercetin as Senolytic Drugs Improve Fat Deposition and Exhibit Antifibrotic Effects in the Medaka Metabolic Dysfunction-Associated Steatotic Liver Disease Model.

Although both of them have no significant difference, Pparα showed an increasing trend in the treatment group, whereas Pparγ showed a decreasing trend in both HFD and treatment groups. 3.5.

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Similarly, Mmp2 expression showed an increasing trend of 1.63 ± 0.75-fold in the HFD group and an improving trend of 0.71 ± 0.79-fold in the treatment group, although the difference was insignificant ( p = 0.3294).

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