Evaluating the Efficacy of Levetiracetam on Non-Cognitive Symptoms and Pathology in a Tau Mouse Model.

The results of our short-term study show a reduction in the hyperactive phenotype in Tg4510 mice, which induced an increasing trend in the fat mass of these mice.

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The Western blot analysis of the hippocampus revealed a decreasing trend in total Tau and phosphorylated Tau at Ser199/202 in Tg4510 mice treated with levetiracetam when compared to controls.

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