Transcriptome analysis reveals molecular targets of erythrocyte invasion phenotype diversity in natural <i>Plasmodium falciparum</i> isolates from Cameroon.

Expression of Rh5 and msp6 was not significantly different between the two clusters of isolates and could thus be considered as part of the “schizont stage gene expression signatures.” In addition, strong positive and highly significant Spearman’s rank correlation coefficients ( r) were observed between the log2 transformed transcript abundance estimates obtained with RT-qPCR and RNAseq and ranged from r =0.898 for the clag3.2 gene to r =0.96 for the eba175 gene ( Figure 4B ).

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