However, to focus on the most significant hits, stricter cut-off parameters of q < 0.0001 and log 2 CPM > 3 for at least one meropenem concentration were used, ensuring all loci meeting these criteria had a highly significant change in transposon abundance between conditions and were represented by many mutants.
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A whole-genome assay identifies four principal gene functions that confer tolerance of meropenem stress upon <i>Escherichia coli</i>.
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