Flavonoids of <i>Tetrastigma hemsleyanum</i> Diels et Gilg Against Acute Hepatic Injury by Blocking PI3K/AKT Signaling Pathway.

When compared with the MOD group, the THF-H group showed highly significant decreases in CRP, IL6, and TNF-α levels and highly significant increase in IL-10 levels ( Figure 6 A–D, p < 0.01); in the THF-M group, the level of IL-10 was highly significantly increased ( Figure 6 C, p < 0.01), and the level of TNF- α was significantly decreased ( Figure 6 D, p < 0.05); the levels of IL-6 and TNF-α inflammatory factors were extremely significantly decreased in the THF-L group ( Figure 6 B,D, p < 0.01).

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