Horticultural activity in soil inoculated with Streptomyces rimosus improved depressive mood with altered electroencephalogram and serum metabolism in adults.

GC-TOF-MS analysis identified 44 altered serum metabolites, showing an increasing trend in succinate, glycolate, glycerate, acetate, palmitate, myristate, laurate, caprynate, and octanoate, which are related to the citrate cycle, glyoxylate and dicarboxylate metabolism, and fatty acid biosynthesis.

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Glucose exhibited a decreasing trend in the SRI group, indicating increased energy metabolism, as indicated by both glucose consumption and elevated levels of metabolites linked to the TCA cycle and glyoxylate and dicarboxylate metabolism.

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