Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity.

Additionally, IFN-γ-producing CD8 + T cells displayed a decreasing trend with no significant difference, while decreased proportions of IFN-γ + CD8 + T cells among CD45 + cells were observed in metformin-treated IgA wt mice ( p = 0.0298) ( Figure 5e–i , Figure S8g – i, Figure S9).

also in 29,529 other papers